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Active Dendritic Cell Immunotherapy Photo from The Czerniecki Lab

Dr. BRIAN CZERNIECKI, MD, PhD.

Chair, Dept of Breast Oncology, Moffitt Cancer Center,
Professor Emeritus of the University of Pennsylvania


Dr. Brian Czerniecki is Chair and Senior Member in the Moffitt Cancer Center Department of Breast Oncology. Dr. Czerniecki received his BS in Biochemistry from the University of Maine and his MD from the University of Medicine and Dentistry of New Jersey (UMDNJ), Robert Wood Johnson Medical School, and his PhD from UMDNJ-Robert Wood Johnson and Rutgers University. Dr. Czerniecki completed his general surgical residency at The Ohio State University and was Surgical Oncology Fellow at the NCI with Dr. Steven Rosenberg prior to his position at the University of Pennsylvania, Philadelphia.

While at the University of Pennsylvania, Dr. Czerniecki served as Professor of Surgery, Perelman School of Medicine; Attending Surgeon, Department of Surgery, Hospital of the University of Pennsylvania; and Co-Director of the Rena Rowan Breast Center–Recruitment and Center Expansion. His research interests focus on dendritic cell biology and interactions with T cells. He has developed dendritic cell vaccines for the treatment of cancer. He is involved with several clinical trials for treating patients with early breast cancer with dendritic cell vaccines. Dr. Czerniecki’s research goal is the development of vaccines for the prevention of breast and other solid-tumor cancers. Toward that end, he is working on identifying molecular targets in early breast cancer that can be used to prevent invasion and metastasis. Dr. Czerniecki has more than 100 publications and is recognized nationally for his contribution to the development of sentinel lymph node mapping, a procedure for determining the spread of cancer into lymph nodes that is less invasive than diagnostic surgery.

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SCIENCE IS WINNING

OUTSMARTING CANCER

NON-TOXIC DENDRITIC CELL Immunotherapy EXPLAINED

SAVING REAL LIVES

NOT TOMORROW...TODAY!
The immune system’s most important job is to protect the body from infection. In order to accomplish this, it must first make distinctions between invading microbes and normal bodily cells.  Then it must specifically attack and eliminate the intruders while scrupulously avoiding assaults on normal cells and tissues of the body. The reason that this vital bodily defense system is seldom a natural enemy to cancer is that malignant cells very closely resemble normal healthy ones, at least so far as the immune system is concerned. Because of this, the immune system perceives no threat from cancer and usually does not attack. Therefore, the trick to getting the immune system to violently oppose cancer may lie in tricking it into perceiving cancer as an infection that requires immediate action.

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Painting by World Renowned Artist and Loyal Supporter Jane Bazinet

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